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| Player | Team | W | L | ERA | G | GS | CG | SV | IP | H | R | ER | HR | BB | SO | BB/9 | SO/9 | WHIP | G/F |
| M Batista | SEA | 4 | 14 | 6.26 | 44 | 20 | 0 | 1 | 115.0 | 135 | 89 | 80 | 19 | 79 | 73 | 6.18 | 5.71 | 1.86 | 1.12 |
| A Benitez | TOR | 0 | 1 | 5.68 | 8 | 0 | 0 | 0 | 6.1 | 4 | 5 | 4 | 3 | 2 | 9 | 2.95 | 13.28 | 0.95 | 0.57 |
| J Borowski | CLE | 1 | 3 | 7.56 | 18 | 0 | 0 | 6 | 16.2 | 24 | 14 | 14 | 4 | 8 | 9 | 4.44 | 5.00 | 1.92 | 0.41 |
| P Byrd | BOS | 11 | 12 | 4.60 | 30 | 30 | 1 | 0 | 180.0 | 204 | 96 | 92 | 31 | 34 | 82 | 1.70 | 4.10 | 1.32 | 0.82 |
| B Colon | BOS | 4 | 2 | 3.92 | 7 | 7 | 0 | 0 | 39.0 | 44 | 23 | 17 | 5 | 10 | 27 | 2.31 | 6.23 | 1.38 | 0.86 |
| A Embree | OAK | 2 | 5 | 4.96 | 70 | 0 | 0 | 0 | 61.2 | 59 | 36 | 34 | 8 | 30 | 57 | 4.41 | 8.38 | 1.44 | 1.06 |
| K Foulke | OAK | 0 | 3 | 4.06 | 31 | 0 | 0 | 1 | 31.0 | 28 | 14 | 14 | 7 | 13 | 23 | 3.77 | 6.68 | 1.32 | 0.51 |
| E Guardado | MIN | 4 | 4 | 4.15 | 64 | 0 | 0 | 4 | 56.1 | 50 | 26 | 26 | 4 | 19 | 33 | 3.05 | 5.29 | 1.22 | 0.47 |
| L Hawkins | NYY | 1 | 1 | 5.71 | 33 | 0 | 0 | 0 | 41.0 | 42 | 26 | 26 | 3 | 17 | 23 | 3.73 | 5.05 | 1.44 | 1.38 |
| L Hernandez | MIN | 10 | 8 | 5.48 | 23 | 23 | 2 | 0 | 139.2 | 199 | 93 | 85 | 18 | 29 | 54 | 1.88 | 3.49 | 1.63 | 1.17 |
| T Jones | DET | 4 | 1 | 4.97 | 45 | 0 | 0 | 18 | 41.2 | 50 | 30 | 23 | 5 | 18 | 14 | 3.93 | 3.06 | 1.63 | 1.35 |
| E Loaiza | CWS | 0 | 0 | 3.00 | 3 | 0 | 0 | 0 | 3.0 | 3 | 2 | 1 | 1 | 0 | 1 | 0.00 | 3.00 | 1.00 | 1.25 |
| R Mahay | KC | 5 | 0 | 3.48 | 57 | 0 | 0 | 0 | 64.2 | 61 | 27 | 25 | 6 | 29 | 49 | 4.07 | 6.87 | 1.39 | 0.92 |
| T Miller | TB | 2 | 0 | 4.15 | 68 | 0 | 0 | 2 | 43.1 | 39 | 21 | 20 | 2 | 20 | 44 | 4.18 | 9.19 | 1.36 | 0.70 |
| K Millwood | TEX | 9 | 10 | 5.07 | 29 | 29 | 3 | 0 | 168.2 | 220 | 104 | 95 | 18 | 49 | 125 | 2.62 | 6.69 | 1.59 | 0.98 |
| M Mussina | NYY | 20 | 9 | 3.37 | 34 | 34 | 0 | 0 | 200.1 | 214 | 85 | 75 | 17 | 31 | 150 | 1.39 | 6.75 | 1.22 | 1.41 |
| H Nomo | KC | 0 | 0 | 18.69 | 3 | 0 | 0 | 0 | 4.1 | 10 | 9 | 9 | 3 | 4 | 3 | 8.78 | 6.59 | 3.23 | 1.00 |
| D Oliver | LAA | 7 | 1 | 2.88 | 54 | 0 | 0 | 0 | 72.0 | 67 | 24 | 23 | 5 | 16 | 48 | 2.00 | 6.00 | 1.15 | 1.19 |
| T Percival | TB | 2 | 1 | 4.53 | 50 | 0 | 0 | 28 | 45.2 | 29 | 26 | 23 | 9 | 27 | 38 | 5.38 | 7.57 | 1.23 | 0.32 |
| A Pettitte | NYY | 14 | 14 | 4.54 | 33 | 33 | 0 | 0 | 204.0 | 233 | 112 | 103 | 19 | 55 | 158 | 2.43 | 6.97 | 1.41 | 1.62 |
| D Reyes | MIN | 3 | 0 | 2.33 | 75 | 0 | 0 | 0 | 46.1 | 40 | 12 | 12 | 4 | 15 | 39 | 2.93 | 7.61 | 1.19 | 2.13 |
| A Reyes | TB | 2 | 2 | 4.37 | 26 | 0 | 0 | 0 | 22.2 | 21 | 12 | 11 | 2 | 10 | 19 | 4.05 | 7.70 | 1.37 | 0.74 |
| A Rhodes | SEA | 2 | 1 | 2.86 | 36 | 0 | 0 | 1 | 22.0 | 17 | 8 | 7 | 0 | 13 | 26 | 5.32 | 10.64 | 1.36 | 0.58 |
| M Rivera | NYY | 6 | 5 | 1.40 | 64 | 0 | 0 | 39 | 70.2 | 41 | 11 | 11 | 4 | 6 | 77 | 0.77 | 9.87 | 0.67 | 1.41 |
| K Rogers | DET | 9 | 13 | 5.70 | 30 | 30 | 0 | 0 | 173.2 | 212 | 118 | 110 | 22 | 71 | 82 | 3.69 | 4.26 | 1.63 | 1.13 |
| J Tavarez | BOS | 0 | 1 | 6.39 | 9 | 0 | 0 | 0 | 12.2 | 18 | 12 | 9 | 0 | 9 | 6 | 6.64 | 4.43 | 2.13 | 2.30 |
| M Timlin | BOS | 4 | 4 | 5.66 | 47 | 0 | 0 | 1 | 49.1 | 60 | 32 | 31 | 9 | 20 | 32 | 3.67 | 5.87 | 1.62 | 1.34 |
| B Tomko | KC | 2 | 7 | 6.97 | 16 | 10 | 0 | 0 | 60.2 | 80 | 49 | 47 | 11 | 13 | 40 | 1.94 | 5.98 | 1.53 | 1.38 |
| S Trachsel | BAL | 2 | 5 | 8.39 | 10 | 8 | 0 | 0 | 39.2 | 53 | 41 | 37 | 10 | 27 | 16 | 6.20 | 3.67 | 2.02 | 1.15 |
| T Wakefield | BOS | 10 | 11 | 4.13 | 30 | 30 | 1 | 0 | 181.0 | 154 | 89 | 83 | 25 | 60 | 117 | 2.98 | 5.82 | 1.18 | 0.73 |
| J Walker | BAL | 1 | 3 | 6.87 | 59 | 0 | 0 | 0 | 38.0 | 53 | 31 | 29 | 12 | 11 | 24 | 2.61 | 5.68 | 1.68 | 0.60 |
| J Wright | TEX | 8 | 7 | 5.12 | 75 | 0 | 0 | 0 | 84.1 | 93 | 57 | 48 | 5 | 35 | 60 | 3.75 | 6.42 | 1.52 | 2.77 |
| B Ryan | TOR | 2 | 4 | 2.95 | 60 | 0 | 0 | 32 | 58.0 | 46 | 21 | 19 | 4 | 28 | 58 | 4.34 | 9.00 | 1.28 | 0.95 |
| J Washburn | SEA | 5 | 14 | 4.69 | 28 | 26 | 1 | 1 | 153.2 | 174 | 87 | 80 | 19 | 50 | 87 | 2.94 | 5.11 | 1.46 | 0.79 |
| B Corey | BOS | 0 | 0 | 10.50 | 7 | 0 | 0 | 0 | 6.0 | 11 | 7 | 7 | 1 | 3 | 4 | 4.50 | 6.00 | 2.33 | 0.86 |
| S Ponson | NYY | 8 | 5 | 5.04 | 25 | 24 | 1 | 0 | 135.2 | 170 | 89 | 76 | 14 | 48 | 58 | 3.20 | 3.86 | 1.61 | 1.81 |
| J Speier | LAA | 2 | 8 | 5.03 | 62 | 0 | 0 | 0 | 68.0 | 69 | 41 | 38 | 15 | 27 | 56 | 3.57 | 7.41 | 1.41 | 0.84 |
| S Elarton | CLE | 0 | 1 | 3.52 | 8 | 0 | 0 | 0 | 15.1 | 16 | 7 | 6 | 0 | 9 | 15 | 5.36 | 8.94 | 1.63 | 1.31 |
| J Vazquez | CWS | 12 | 16 | 4.67 | 33 | 33 | 1 | 0 | 208.1 | 214 | 113 | 108 | 25 | 61 | 200 | 2.64 | 8.65 | 1.32 | 0.92 |
| C Pavano | NYY | 4 | 2 | 5.77 | 7 | 7 | 0 | 0 | 34.1 | 41 | 23 | 22 | 5 | 10 | 15 | 2.64 | 3.96 | 1.49 | 0.79 |
| C Bradford | TB | 4 | 3 | 2.12 | 68 | 0 | 0 | 0 | 59.1 | 59 | 20 | 14 | 3 | 15 | 17 | 2.28 | 2.59 | 1.25 | 3.00 |
| O Dotel | CWS | 4 | 4 | 3.76 | 72 | 0 | 0 | 1 | 67.0 | 52 | 34 | 28 | 12 | 29 | 92 | 3.90 | 12.36 | 1.21 | 0.81 |
| R Halladay | TOR | 20 | 11 | 2.78 | 34 | 33 | 9 | 0 | 246.0 | 220 | 88 | 76 | 18 | 39 | 206 | 1.43 | 7.54 | 1.05 | 1.77 |
| K Farnsworth | DET | 2 | 3 | 4.48 | 61 | 0 | 0 | 1 | 60.1 | 70 | 32 | 30 | 15 | 22 | 61 | 3.29 | 9.13 | 1.52 | 0.74 |
| F Garcia | DET | 1 | 1 | 4.20 | 3 | 3 | 0 | 0 | 15.0 | 11 | 8 | 7 | 3 | 6 | 12 | 3.60 | 7.20 | 1.13 | 0.88 |
| D Marte | NYY | 1 | 3 | 5.40 | 25 | 0 | 0 | 0 | 18.1 | 14 | 11 | 11 | 1 | 10 | 24 | 4.97 | 11.93 | 1.31 | 0.29 |
| B Seay | DET | 1 | 2 | 4.47 | 60 | 0 | 0 | 0 | 56.1 | 59 | 28 | 28 | 4 | 25 | 58 | 4.01 | 9.30 | 1.49 | 0.81 |
| J Nathan | MIN | 1 | 2 | 1.33 | 68 | 0 | 0 | 39 | 67.2 | 43 | 13 | 10 | 5 | 18 | 74 | 2.41 | 9.91 | 0.90 | 1.30 |
| K Wells | KC | 0 | 1 | 8.71 | 10 | 0 | 0 | 0 | 10.1 | 10 | 10 | 10 | 1 | 11 | 9 | 9.80 | 8.02 | 2.03 | 1.75 |
| A Burnett | TOR | 18 | 10 | 4.07 | 35 | 34 | 1 | 0 | 221.1 | 211 | 109 | 100 | 19 | 86 | 231 | 3.50 | 9.40 | 1.34 | 1.47 |
| J Westbrook | CLE | 1 | 2 | 3.12 | 5 | 5 | 1 | 0 | 34.2 | 33 | 13 | 12 | 5 | 7 | 19 | 1.84 | 5.00 | 1.15 | 1.93 |
| J Bale | KC | 0 | 3 | 4.39 | 13 | 3 | 0 | 0 | 26.2 | 29 | 13 | 13 | 1 | 6 | 14 | 2.06 | 4.81 | 1.31 | 1.87 |
| G Glover | DET | 2 | 3 | 5.30 | 47 | 0 | 0 | 0 | 54.1 | 64 | 33 | 32 | 7 | 22 | 37 | 3.66 | 6.16 | 1.58 | 0.87 |
| M MacDougal | CWS | 0 | 0 | 2.12 | 16 | 0 | 0 | 0 | 17.0 | 16 | 4 | 4 | 0 | 12 | 12 | 6.35 | 6.35 | 1.65 | 1.29 |
| M Ginter | CLE | 1 | 3 | 5.14 | 4 | 4 | 0 | 0 | 21.0 | 25 | 12 | 12 | 3 | 3 | 12 | 1.29 | 5.14 | 1.33 | 1.22 |
| K Snyder | BOS | 0 | 0 | 21.60 | 2 | 0 | 0 | 0 | 1.2 | 2 | 4 | 4 | 1 | 2 | 1 | 15.00 | 7.50 | 2.40 | 1.00 |
| V Padilla | TEX | 14 | 8 | 4.74 | 29 | 29 | 1 | 0 | 171.0 | 185 | 100 | 90 | 26 | 65 | 127 | 3.42 | 6.68 | 1.46 | 1.05 |
| G Meche | KC | 14 | 11 | 3.98 | 34 | 34 | 0 | 0 | 210.1 | 204 | 98 | 93 | 19 | 73 | 183 | 3.13 | 7.84 | 1.32 | 0.81 |
| D Wheeler | TB | 5 | 6 | 3.12 | 70 | 0 | 0 | 13 | 66.1 | 44 | 25 | 23 | 10 | 22 | 53 | 3.00 | 7.22 | 0.99 | 0.43 |
| S Downs | TOR | 0 | 3 | 1.78 | 66 | 0 | 0 | 5 | 70.2 | 54 | 15 | 14 | 3 | 27 | 57 | 3.46 | 7.31 | 1.15 | 3.33 |
| J Grilli | DET | 0 | 1 | 3.29 | 9 | 0 | 0 | 0 | 13.2 | 12 | 5 | 5 | 1 | 7 | 10 | 4.77 | 6.82 | 1.39 | 0.76 |
| S Linebrink | CWS | 2 | 2 | 3.69 | 50 | 0 | 0 | 1 | 46.1 | 41 | 20 | 19 | 8 | 9 | 40 | 1.76 | 7.81 | 1.08 | 0.85 |
| J Benoit | TEX | 3 | 2 | 5.00 | 44 | 0 | 0 | 1 | 45.0 | 40 | 28 | 25 | 6 | 35 | 43 | 7.00 | 8.60 | 1.67 | 0.55 |
| S Shields | LAA | 6 | 4 | 2.70 | 64 | 0 | 0 | 4 | 63.1 | 56 | 29 | 19 | 6 | 29 | 64 | 4.14 | 9.13 | 1.34 | 1.65 |
| J Beckett | BOS | 12 | 10 | 4.03 | 27 | 27 | 1 | 0 | 174.1 | 173 | 80 | 78 | 18 | 34 | 172 | 1.76 | 8.89 | 1.19 | 0.97 |
| J Garland | LAA | 14 | 8 | 4.90 | 32 | 32 | 1 | 0 | 196.2 | 237 | 116 | 107 | 23 | 59 | 90 | 2.71 | 4.13 | 1.51 | 1.56 |
| M Buehrle | CWS | 15 | 12 | 3.79 | 34 | 34 | 1 | 0 | 218.2 | 240 | 106 | 92 | 22 | 52 | 140 | 2.14 | 5.77 | 1.34 | 1.63 |
| C Sabathia | CLE | 6 | 8 | 3.83 | 18 | 18 | 3 | 0 | 122.1 | 117 | 54 | 52 | 13 | 34 | 123 | 2.51 | 9.07 | 1.23 | 1.03 |
| R Dickey | SEA | 5 | 8 | 5.21 | 32 | 14 | 0 | 0 | 112.1 | 124 | 65 | 65 | 15 | 51 | 58 | 4.09 | 4.66 | 1.56 | 1.19 |
| J Parrish | TOR | 1 | 1 | 4.04 | 13 | 6 | 0 | 0 | 42.1 | 47 | 19 | 19 | 5 | 15 | 21 | 3.21 | 4.49 | 1.46 | 0.92 |
| G Balfour | TB | 6 | 2 | 1.54 | 51 | 0 | 0 | 4 | 58.1 | 28 | 10 | 10 | 3 | 24 | 82 | 3.72 | 12.70 | 0.89 | 0.45 |
| J Rincon | CLE | 3 | 3 | 5.86 | 47 | 0 | 0 | 0 | 55.1 | 67 | 39 | 36 | 8 | 24 | 39 | 3.92 | 6.37 | 1.64 | 0.90 |
| B Duckworth | KC | 3 | 3 | 4.50 | 7 | 7 | 0 | 0 | 38.0 | 38 | 20 | 19 | 2 | 19 | 20 | 4.50 | 4.74 | 1.50 | 1.07 |
| C Silva | SEA | 4 | 15 | 6.46 | 28 | 28 | 1 | 0 | 153.1 | 213 | 114 | 110 | 20 | 32 | 69 | 1.88 | 4.06 | 1.60 | 1.16 |
| S Loux | LAA | 0 | 0 | 2.81 | 7 | 0 | 0 | 0 | 16.0 | 16 | 6 | 5 | 1 | 2 | 4 | 1.13 | 2.25 | 1.13 | 4.00 |
| H Ramirez | CWS | 1 | 4 | 4.34 | 32 | 0 | 0 | 0 | 37.1 | 45 | 20 | 18 | 1 | 9 | 13 | 2.18 | 3.15 | 1.45 | 1.50 |
| D Moseley | LAA | 2 | 4 | 6.79 | 12 | 10 | 0 | 0 | 50.1 | 70 | 38 | 38 | 6 | 20 | 37 | 3.59 | 6.65 | 1.79 | 1.41 |
| J Julio | CLE | 0 | 0 | 5.60 | 15 | 0 | 0 | 0 | 17.2 | 18 | 11 | 11 | 3 | 11 | 15 | 5.76 | 7.85 | 1.64 | 0.71 |
| J Burke | SEA | 0 | 1 | 9.00 | 1 | 0 | 0 | 0 | 1.0 | 1 | 1 | 1 | 0 | 0 | 0 | 0.00 | 0.00 | 1.00 | 0.50 |
| J Duchscherer | OAK | 10 | 8 | 2.54 | 22 | 22 | 1 | 0 | 141.2 | 107 | 45 | 40 | 11 | 34 | 95 | 2.17 | 6.06 | 1.00 | 0.96 |
| C Fossum | DET | 3 | 1 | 5.66 | 31 | 0 | 0 | 0 | 41.1 | 44 | 26 | 26 | 4 | 18 | 28 | 3.94 | 6.13 | 1.50 | 1.16 |
| J Jennings | TEX | 0 | 5 | 8.56 | 6 | 6 | 0 | 0 | 27.1 | 35 | 27 | 26 | 8 | 18 | 12 | 5.98 | 3.99 | 1.94 | 1.37 |
| R Bauer | CLE | 0 | 0 | 13.50 | 4 | 0 | 0 | 0 | 6.0 | 10 | 9 | 9 | 1 | 3 | 4 | 4.50 | 6.00 | 2.17 | 0.56 |
| F Beltran | DET | 1 | 0 | 4.85 | 11 | 0 | 0 | 0 | 13.0 | 13 | 7 | 7 | 3 | 6 | 9 | 4.15 | 6.23 | 1.46 | 2.00 |
| B Donnelly | CLE | 1 | 0 | 8.56 | 15 | 0 | 0 | 0 | 13.2 | 20 | 13 | 13 | 2 | 10 | 8 | 6.82 | 5.45 | 2.20 | 0.67 |
| J Lackey | LAA | 12 | 5 | 3.75 | 24 | 24 | 3 | 0 | 163.1 | 161 | 71 | 68 | 26 | 40 | 130 | 2.21 | 7.17 | 1.23 | 1.25 |
| J Putz | SEA | 6 | 5 | 3.88 | 47 | 0 | 0 | 15 | 46.1 | 46 | 20 | 20 | 4 | 28 | 56 | 5.47 | 10.93 | 1.60 | 0.78 |
| M Thornton | CWS | 5 | 3 | 2.67 | 74 | 0 | 0 | 1 | 67.1 | 48 | 20 | 20 | 5 | 19 | 77 | 2.55 | 10.33 | 1.00 | 1.49 |
| M Guerrier | MIN | 6 | 9 | 5.19 | 76 | 0 | 0 | 1 | 76.1 | 84 | 47 | 44 | 12 | 37 | 59 | 4.38 | 6.98 | 1.59 | 1.20 |
| J Veras | NYY | 5 | 3 | 3.59 | 60 | 0 | 0 | 0 | 57.2 | 52 | 23 | 23 | 7 | 29 | 63 | 4.56 | 9.91 | 1.40 | 0.88 |
| F Rodney | DET | 0 | 6 | 4.91 | 38 | 0 | 0 | 13 | 40.1 | 34 | 22 | 22 | 3 | 30 | 49 | 6.73 | 11.00 | 1.59 | 1.15 |
| E Bedard | SEA | 6 | 4 | 3.67 | 15 | 15 | 0 | 0 | 81.0 | 70 | 38 | 33 | 9 | 37 | 72 | 4.11 | 8.00 | 1.32 | 1.00 |
| J Diaz | TEX | 0 | 0 | 0.00 | 1 | 0 | 0 | 0 | 1.0 | 1 | 1 | 0 | 0 | 1 | 2 | 9.00 | 18.00 | 2.00 | 0.00 |
| F German | TEX | 1 | 3 | 2.08 | 17 | 0 | 0 | 0 | 21.2 | 18 | 5 | 5 | 0 | 13 | 15 | 5.52 | 6.37 | 1.43 | 0.71 |
| B Traber | NYY | 0 | 0 | 7.02 | 19 | 0 | 0 | 0 | 16.2 | 23 | 13 | 13 | 3 | 7 | 11 | 3.89 | 6.11 | 1.80 | 1.38 |
| J Peralta | KC | 1 | 2 | 5.98 | 40 | 0 | 0 | 0 | 52.2 | 56 | 37 | 35 | 15 | 14 | 38 | 2.41 | 6.55 | 1.33 | 0.75 |
| F Francisco | TEX | 3 | 5 | 3.13 | 58 | 0 | 0 | 5 | 63.1 | 47 | 24 | 22 | 7 | 26 | 83 | 3.71 | 11.84 | 1.15 | 0.59 |
| A Brown | OAK | 1 | 0 | 3.09 | 31 | 0 | 0 | 0 | 35.0 | 23 | 13 | 12 | 3 | 21 | 28 | 5.40 | 7.20 | 1.26 | 0.63 |
| C Bootcheck | LAA | 0 | 1 | 10.13 | 10 | 0 | 0 | 0 | 16.0 | 30 | 18 | 18 | 2 | 12 | 14 | 6.75 | 7.88 | 2.63 | 0.62 |
| B Jenks | CWS | 3 | 1 | 2.63 | 57 | 0 | 0 | 30 | 61.2 | 51 | 18 | 18 | 3 | 17 | 38 | 2.50 | 5.59 | 1.10 | 1.96 |
| F Rodriguez | LAA | 2 | 3 | 2.24 | 76 | 0 | 0 | 62 | 68.1 | 54 | 21 | 17 | 4 | 34 | 77 | 4.49 | 10.18 | 1.29 | 0.97 |
| J Bulger | LAA | 0 | 0 | 7.31 | 14 | 0 | 0 | 0 | 16.0 | 15 | 13 | 13 | 3 | 9 | 20 | 5.06 | 11.25 | 1.50 | 0.87 |
| K Saarloos | OAK | 1 | 0 | 5.47 | 8 | 1 | 0 | 0 | 26.1 | 37 | 17 | 16 | 2 | 4 | 12 | 1.38 | 4.14 | 1.56 | 1.72 |
| C Lee | CLE | 22 | 3 | 2.54 | 31 | 31 | 4 | 0 | 223.1 | 214 | 68 | 63 | 12 | 34 | 170 | 1.37 | 6.86 | 1.11 | 1.10 |
| R Bukvich | BAL | 0 | 0 | 6.75 | 4 | 0 | 0 | 0 | 5.1 | 9 | 4 | 4 | 2 | 6 | 5 | 10.59 | 8.82 | 2.81 | 1.20 |
| N Robertson | DET | 7 | 11 | 6.35 | 32 | 28 | 0 | 0 | 168.2 | 218 | 124 | 119 | 26 | 62 | 108 | 3.32 | 5.78 | 1.66 | 1.30 |
| B Tallet | TOR | 1 | 2 | 2.88 | 51 | 0 | 0 | 0 | 56.1 | 52 | 19 | 18 | 4 | 22 | 47 | 3.53 | 7.54 | 1.31 | 1.12 |
| J Guthrie | BAL | 10 | 12 | 3.63 | 30 | 30 | 1 | 0 | 190.2 | 176 | 82 | 77 | 24 | 58 | 120 | 2.74 | 5.68 | 1.23 | 1.12 |
| C Wang | NYY | 8 | 2 | 4.07 | 15 | 15 | 1 | 0 | 95.0 | 90 | 44 | 43 | 4 | 35 | 54 | 3.32 | 5.12 | 1.32 | 1.70 |
| J Gobble | KC | 0 | 2 | 8.81 | 39 | 0 | 0 | 1 | 31.2 | 39 | 31 | 31 | 5 | 23 | 27 | 6.63 | 7.79 | 1.96 | 0.39 |
| F Cabrera | BAL | 2 | 1 | 5.40 | 22 | 0 | 0 | 0 | 28.1 | 32 | 18 | 17 | 9 | 17 | 31 | 5.44 | 9.93 | 1.73 | 0.43 |
| F Cruceta | DET | 0 | 3 | 5.40 | 13 | 0 | 0 | 0 | 11.2 | 13 | 8 | 7 | 2 | 10 | 11 | 8.04 | 8.84 | 1.97 | 1.67 |
| D Cabrera | BAL | 8 | 10 | 5.25 | 30 | 30 | 2 | 0 | 180.0 | 199 | 109 | 105 | 24 | 90 | 95 | 4.50 | 4.75 | 1.61 | 1.33 |
| C Waters | BAL | 3 | 5 | 5.01 | 11 | 11 | 1 | 0 | 64.2 | 70 | 38 | 36 | 9 | 29 | 33 | 4.07 | 4.63 | 1.53 | 1.33 |
| K Calero | OAK | 0 | 0 | 3.86 | 5 | 0 | 0 | 0 | 4.2 | 3 | 3 | 2 | 0 | 3 | 7 | 6.43 | 15.00 | 1.29 | 0.17 |
| G Aquino | BAL | 0 | 0 | 12.54 | 9 | 0 | 0 | 0 | 9.1 | 17 | 13 | 13 | 1 | 9 | 9 | 8.90 | 8.90 | 2.79 | 0.55 |
| D Carrasco | CWS | 1 | 0 | 3.96 | 31 | 0 | 0 | 0 | 38.2 | 30 | 17 | 17 | 2 | 14 | 30 | 3.30 | 7.07 | 1.14 | 1.59 |
| J Lopez | BOS | 2 | 0 | 2.43 | 70 | 0 | 0 | 0 | 59.1 | 53 | 18 | 16 | 4 | 27 | 38 | 4.11 | 5.79 | 1.35 | 2.63 |
| A Lopez | DET | 4 | 1 | 3.55 | 48 | 0 | 0 | 0 | 78.2 | 86 | 33 | 31 | 9 | 22 | 61 | 2.53 | 7.02 | 1.37 | 0.50 |
| J Contreras | CWS | 7 | 6 | 4.54 | 20 | 20 | 1 | 0 | 121.0 | 130 | 64 | 61 | 12 | 35 | 70 | 2.60 | 5.21 | 1.36 | 1.46 |
| B Bonser | MIN | 3 | 7 | 5.93 | 47 | 12 | 0 | 0 | 118.1 | 139 | 87 | 78 | 16 | 36 | 97 | 2.74 | 7.39 | 1.48 | 0.89 |
| J Bonderman | DET | 3 | 4 | 4.29 | 12 | 12 | 0 | 0 | 71.1 | 75 | 39 | 34 | 9 | 36 | 44 | 4.56 | 5.57 | 1.56 | 1.11 |
| Z Greinke | KC | 13 | 10 | 3.47 | 32 | 32 | 1 | 0 | 202.1 | 202 | 87 | 78 | 21 | 56 | 183 | 2.49 | 8.15 | 1.28 | 1.04 |
| R Harden | OAK | 5 | 1 | 2.34 | 13 | 13 | 0 | 0 | 77.0 | 57 | 21 | 20 | 5 | 31 | 92 | 3.62 | 10.75 | 1.14 | 0.48 |
| G Floyd | CWS | 17 | 8 | 3.84 | 33 | 33 | 1 | 0 | 206.1 | 190 | 107 | 88 | 30 | 70 | 145 | 3.06 | 6.33 | 1.26 | 0.98 |
| B Bullington | CLE | 0 | 2 | 4.91 | 3 | 2 | 0 | 0 | 14.2 | 15 | 9 | 8 | 4 | 2 | 12 | 1.27 | 7.61 | 1.16 | 1.46 |
| S Camp | TOR | 3 | 1 | 4.12 | 40 | 0 | 0 | 0 | 39.1 | 40 | 18 | 18 | 2 | 11 | 31 | 2.53 | 7.14 | 1.30 | 2.11 |
| D Willis | DET | 0 | 2 | 9.38 | 8 | 7 | 0 | 0 | 24.0 | 18 | 25 | 25 | 4 | 35 | 18 | 13.13 | 6.75 | 2.21 | 1.08 |
| A Loewen | BAL | 0 | 2 | 8.02 | 7 | 4 | 0 | 0 | 21.1 | 25 | 19 | 19 | 5 | 18 | 14 | 7.68 | 5.97 | 2.02 | 1.00 |
| D Bautista | DET | 0 | 1 | 3.32 | 16 | 0 | 0 | 0 | 19.0 | 15 | 7 | 7 | 1 | 14 | 10 | 6.63 | 4.74 | 1.53 | 0.55 |
| E Jackson | TB | 14 | 11 | 4.42 | 32 | 31 | 0 | 0 | 183.1 | 199 | 91 | 90 | 23 | 77 | 108 | 3.78 | 5.31 | 1.51 | 0.84 |
| E Santana | LAA | 16 | 7 | 3.49 | 32 | 32 | 2 | 0 | 219.0 | 198 | 89 | 85 | 23 | 47 | 214 | 1.93 | 8.79 | 1.12 | 0.79 |
| R Betancourt | CLE | 3 | 4 | 5.07 | 69 | 0 | 0 | 4 | 71.0 | 76 | 41 | 40 | 11 | 25 | 64 | 3.17 | 8.11 | 1.42 | 0.54 |
| R Corcoran | SEA | 6 | 2 | 3.22 | 50 | 0 | 0 | 3 | 72.2 | 65 | 31 | 26 | 1 | 36 | 39 | 4.49 | 4.86 | 1.39 | 3.02 |
| C Gaudin | OAK | 5 | 3 | 3.59 | 26 | 6 | 0 | 0 | 62.2 | 63 | 29 | 25 | 6 | 17 | 44 | 2.46 | 6.37 | 1.28 | 1.06 |
| E Ramirez | TEX | 0 | 1 | 30.37 | 1 | 0 | 0 | 0 | 2.2 | 8 | 9 | 9 | 1 | 2 | 1 | 8.18 | 4.09 | 3.75 | 0.17 |
| A Simon | BAL | 0 | 0 | 6.23 | 4 | 1 | 0 | 0 | 13.0 | 16 | 10 | 9 | 4 | 2 | 8 | 1.38 | 5.54 | 1.38 | 2.56 |
| B Wolfe | TOR | 0 | 2 | 2.45 | 20 | 0 | 0 | 0 | 22.0 | 18 | 6 | 6 | 2 | 6 | 14 | 2.45 | 5.73 | 1.09 | 1.32 |
| J Blanton | OAK | 5 | 12 | 4.96 | 20 | 20 | 0 | 0 | 127.0 | 145 | 74 | 70 | 12 | 35 | 62 | 2.48 | 4.39 | 1.42 | 1.31 |
| D Sarfate | BAL | 4 | 3 | 4.74 | 57 | 4 | 0 | 0 | 79.2 | 62 | 47 | 42 | 8 | 62 | 86 | 7.05 | 9.77 | 1.56 | 0.82 |
| S Dohmann | TB | 2 | 0 | 6.14 | 12 | 0 | 0 | 0 | 14.2 | 18 | 10 | 10 | 2 | 7 | 12 | 4.44 | 7.61 | 1.70 | 1.58 |
| J Frasor | TOR | 1 | 2 | 4.18 | 49 | 0 | 0 | 0 | 47.1 | 36 | 23 | 22 | 4 | 32 | 42 | 6.11 | 8.03 | 1.44 | 0.87 |
| T Pena | KC | 0 | 0 | 0.00 | 1 | 0 | 0 | 0 | 1.0 | 0 | 0 | 0 | 0 | 0 | 1 | 0.00 | 9.00 | 0.00 | 1.00 |
| J Woods | SEA | 0 | 0 | 6.16 | 15 | 0 | 0 | 0 | 19.0 | 22 | 13 | 13 | 5 | 11 | 9 | 5.21 | 4.26 | 1.74 | 0.57 |
| B Bass | BAL | 4 | 4 | 4.84 | 49 | 4 | 0 | 1 | 89.1 | 98 | 55 | 48 | 12 | 31 | 45 | 3.13 | 4.55 | 1.44 | 2.25 |
| C Baek | SEA | 0 | 1 | 5.40 | 10 | 1 | 0 | 0 | 30.0 | 28 | 18 | 18 | 6 | 13 | 15 | 3.90 | 4.50 | 1.37 | 0.78 |
| D McGowan | TOR | 6 | 7 | 4.37 | 19 | 19 | 1 | 0 | 111.1 | 115 | 60 | 54 | 9 | 38 | 85 | 3.08 | 6.89 | 1.37 | 1.03 |
| B Bruney | NYY | 3 | 0 | 1.83 | 32 | 1 | 0 | 1 | 34.1 | 18 | 7 | 7 | 2 | 16 | 33 | 4.22 | 8.71 | 0.99 | 0.73 |
| R Ramirez | KC | 3 | 2 | 2.64 | 71 | 0 | 0 | 1 | 71.2 | 57 | 23 | 21 | 2 | 31 | 70 | 3.92 | 8.85 | 1.23 | 1.25 |
| L DiNardo | OAK | 1 | 2 | 7.43 | 11 | 2 | 0 | 0 | 23.0 | 31 | 20 | 19 | 3 | 13 | 12 | 5.09 | 4.70 | 1.91 | 2.33 |
| J Crain | MIN | 5 | 4 | 3.59 | 66 | 0 | 0 | 0 | 62.2 | 62 | 29 | 25 | 6 | 24 | 50 | 3.47 | 7.23 | 1.37 | 0.88 |
| D Aardsma | BOS | 4 | 2 | 5.55 | 47 | 0 | 0 | 0 | 48.2 | 49 | 32 | 30 | 4 | 35 | 49 | 6.54 | 9.15 | 1.73 | 1.29 |
| G Sherrill | BAL | 3 | 5 | 4.73 | 57 | 0 | 0 | 31 | 53.1 | 47 | 28 | 28 | 6 | 33 | 58 | 5.59 | 9.83 | 1.50 | 0.55 |
| B Gordon | TEX | 0 | 0 | 2.25 | 3 | 0 | 0 | 0 | 4.0 | 4 | 1 | 1 | 0 | 0 | 1 | 0.00 | 2.25 | 1.00 | 0.22 |
| D Nippert | TEX | 3 | 5 | 6.40 | 20 | 6 | 0 | 0 | 71.2 | 92 | 52 | 51 | 10 | 37 | 55 | 4.68 | 6.95 | 1.80 | 0.68 |
| S Kazmir | TB | 12 | 8 | 3.49 | 27 | 27 | 0 | 0 | 152.1 | 123 | 61 | 59 | 23 | 70 | 166 | 4.14 | 9.82 | 1.27 | 0.59 |
| L Cormier | BAL | 3 | 3 | 4.02 | 45 | 1 | 0 | 1 | 71.2 | 78 | 36 | 32 | 4 | 34 | 46 | 4.30 | 5.81 | 1.56 | 1.93 |
| J Danks | CWS | 12 | 9 | 3.32 | 33 | 33 | 0 | 0 | 195.0 | 182 | 74 | 72 | 15 | 57 | 159 | 2.63 | 7.34 | 1.23 | 1.07 |
| R Hernandez | CLE | 8 | 7 | 5.44 | 22 | 22 | 1 | 0 | 120.2 | 126 | 80 | 73 | 7 | 70 | 58 | 5.24 | 4.34 | 1.62 | 3.11 |
| S Casilla | OAK | 2 | 1 | 3.93 | 51 | 0 | 0 | 2 | 50.1 | 60 | 22 | 22 | 5 | 20 | 43 | 3.59 | 7.72 | 1.59 | 1.12 |
| F Hernandez | SEA | 9 | 11 | 3.45 | 31 | 31 | 2 | 0 | 200.2 | 198 | 85 | 77 | 17 | 80 | 175 | 3.60 | 7.87 | 1.39 | 1.69 |
| D Meyer | OAK | 0 | 4 | 7.48 | 11 | 4 | 0 | 0 | 27.2 | 35 | 28 | 23 | 6 | 14 | 20 | 4.63 | 6.62 | 1.77 | 0.47 |
| K Loe | TEX | 1 | 0 | 3.23 | 14 | 0 | 0 | 0 | 30.2 | 36 | 18 | 11 | 3 | 8 | 20 | 2.38 | 5.96 | 1.43 | 1.25 |
| B League | TOR | 1 | 2 | 2.18 | 31 | 0 | 0 | 1 | 33.0 | 28 | 9 | 8 | 2 | 15 | 23 | 4.09 | 6.27 | 1.30 | 3.22 |
| J Verlander | DET | 11 | 17 | 4.84 | 33 | 33 | 1 | 0 | 201.0 | 195 | 119 | 108 | 18 | 87 | 163 | 3.90 | 7.30 | 1.40 | 0.82 |
| J Howell | TB | 6 | 1 | 2.22 | 64 | 0 | 0 | 3 | 89.1 | 62 | 29 | 22 | 6 | 39 | 92 | 3.94 | 9.29 | 1.13 | 1.65 |
| D Rasner | NYY | 5 | 10 | 5.40 | 24 | 20 | 0 | 0 | 113.1 | 135 | 74 | 68 | 14 | 39 | 67 | 3.10 | 5.33 | 1.54 | 0.98 |
| J Carlson | TOR | 7 | 2 | 2.25 | 69 | 0 | 0 | 2 | 60.0 | 41 | 16 | 15 | 6 | 21 | 55 | 3.15 | 8.25 | 1.03 | 0.76 |
| F Liriano | MIN | 6 | 4 | 3.91 | 14 | 14 | 0 | 0 | 76.0 | 74 | 40 | 33 | 7 | 32 | 67 | 3.79 | 7.93 | 1.39 | 0.89 |
| R Tejeda | KC | 2 | 2 | 3.97 | 29 | 1 | 0 | 0 | 45.1 | 27 | 23 | 20 | 4 | 24 | 45 | 4.79 | 8.98 | 1.13 | 0.54 |
| J Saunders | LAA | 17 | 7 | 3.41 | 31 | 31 | 1 | 0 | 198.0 | 187 | 82 | 75 | 21 | 53 | 103 | 2.41 | 4.68 | 1.21 | 1.24 |
| D Lowery | KC | 0 | 0 | 10.38 | 5 | 0 | 0 | 0 | 4.1 | 6 | 5 | 5 | 2 | 2 | 6 | 4.39 | 13.17 | 1.85 | 0.75 |
| Y Bazardo | DET | 0 | 0 | 24.00 | 3 | 0 | 0 | 0 | 3.0 | 7 | 8 | 8 | 0 | 5 | 3 | 15.00 | 9.00 | 4.00 | 1.50 |
| R Messenger | SEA | 0 | 0 | 3.55 | 13 | 0 | 0 | 1 | 12.2 | 16 | 5 | 5 | 1 | 5 | 7 | 3.69 | 5.16 | 1.66 | 0.53 |
| J Hammel | TB | 4 | 4 | 4.60 | 40 | 5 | 0 | 2 | 78.1 | 83 | 45 | 40 | 11 | 35 | 44 | 4.03 | 5.07 | 1.51 | 1.25 |
| B Burres | BAL | 7 | 10 | 6.04 | 31 | 22 | 0 | 0 | 129.2 | 165 | 90 | 87 | 17 | 50 | 63 | 3.48 | 4.39 | 1.66 | 0.75 |
| J Oviedo | KC | 4 | 1 | 2.98 | 45 | 0 | 0 | 0 | 48.1 | 45 | 19 | 16 | 2 | 15 | 26 | 2.81 | 4.86 | 1.24 | 0.79 |
| N Masset | CWS | 1 | 0 | 4.63 | 32 | 1 | 0 | 1 | 44.2 | 55 | 26 | 23 | 4 | 21 | 32 | 4.28 | 6.52 | 1.70 | 2.52 |
| J Rupe | TEX | 3 | 1 | 5.14 | 46 | 0 | 0 | 0 | 89.1 | 93 | 52 | 51 | 8 | 46 | 53 | 4.65 | 5.35 | 1.56 | 1.32 |
| M Delcarmen | BOS | 1 | 2 | 3.27 | 73 | 0 | 0 | 2 | 74.1 | 55 | 28 | 27 | 5 | 28 | 72 | 3.40 | 8.74 | 1.12 | 1.28 |
| L Mendoza | TEX | 3 | 8 | 8.67 | 25 | 11 | 0 | 1 | 63.1 | 97 | 74 | 61 | 7 | 25 | 35 | 3.57 | 4.99 | 1.93 | 1.38 |
| C Smith | BOS | 1 | 0 | 7.85 | 12 | 0 | 0 | 0 | 18.1 | 18 | 16 | 16 | 6 | 7 | 13 | 3.48 | 6.46 | 1.36 | 0.52 |
| K Davies | KC | 9 | 7 | 4.06 | 21 | 21 | 0 | 0 | 113.0 | 121 | 57 | 51 | 10 | 43 | 71 | 3.42 | 5.65 | 1.45 | 0.90 |
| H Street | OAK | 7 | 5 | 3.73 | 63 | 0 | 0 | 18 | 70.0 | 58 | 29 | 29 | 6 | 27 | 69 | 3.47 | 8.87 | 1.21 | 0.86 |
| R Rowland-Smith | SEA | 5 | 3 | 3.42 | 47 | 12 | 0 | 2 | 118.1 | 114 | 49 | 45 | 13 | 48 | 77 | 3.66 | 5.87 | 1.37 | 0.86 |
| S Green | SEA | 4 | 5 | 4.67 | 72 | 0 | 0 | 1 | 79.0 | 80 | 47 | 41 | 3 | 36 | 62 | 4.10 | 7.06 | 1.47 | 2.93 |
| A Reyes | CLE | 2 | 1 | 1.83 | 6 | 6 | 0 | 0 | 34.1 | 31 | 7 | 7 | 2 | 12 | 15 | 3.17 | 3.96 | 1.25 | 1.07 |
| S Baker | MIN | 11 | 4 | 3.45 | 28 | 28 | 0 | 0 | 172.1 | 161 | 66 | 66 | 20 | 42 | 141 | 2.20 | 7.37 | 1.18 | 0.58 |
| B McCarthy | TEX | 1 | 1 | 4.09 | 5 | 5 | 0 | 0 | 22.0 | 20 | 11 | 10 | 3 | 8 | 10 | 3.27 | 4.09 | 1.27 | 0.44 |
| Z Miner | DET | 8 | 5 | 4.27 | 45 | 13 | 0 | 0 | 118.0 | 118 | 60 | 56 | 10 | 46 | 62 | 3.51 | 4.73 | 1.39 | 1.14 |
| J Niemann | TB | 2 | 2 | 5.06 | 5 | 2 | 0 | 0 | 16.0 | 18 | 12 | 9 | 3 | 8 | 14 | 4.50 | 7.88 | 1.63 | 1.12 |
| D Giese | NYY | 1 | 3 | 3.53 | 20 | 3 | 0 | 0 | 43.1 | 39 | 22 | 17 | 3 | 14 | 29 | 2.92 | 6.06 | 1.22 | 0.45 |
| J Accardo | TOR | 0 | 3 | 6.57 | 16 | 0 | 0 | 4 | 12.1 | 15 | 10 | 9 | 1 | 4 | 5 | 2.98 | 3.72 | 1.54 | 1.00 |
| Z Jackson | CLE | 2 | 3 | 5.60 | 9 | 9 | 0 | 0 | 54.2 | 64 | 36 | 34 | 7 | 14 | 30 | 2.32 | 4.98 | 1.43 | 1.53 |
| A Castillo | BAL | 1 | 0 | 3.81 | 28 | 0 | 0 | 0 | 26.0 | 27 | 11 | 11 | 3 | 10 | 23 | 3.46 | 7.96 | 1.42 | 1.20 |
| A Serrano | LAA | 0 | 0 | 0.00 | 1 | 0 | 0 | 0 | 1.0 | 1 | 0 | 0 | 0 | 0 | 1 | 0.00 | 9.00 | 1.00 | 0.00 |
| W Madrigal | TEX | 0 | 2 | 4.75 | 31 | 1 | 0 | 1 | 36.0 | 36 | 22 | 19 | 4 | 14 | 22 | 3.50 | 5.50 | 1.39 | 0.73 |
| E Bonine | DET | 2 | 1 | 5.40 | 5 | 5 | 0 | 0 | 26.2 | 36 | 19 | 16 | 3 | 5 | 9 | 1.72 | 3.09 | 1.54 | 1.92 |
| N Adenhart | LAA | 1 | 0 | 9.00 | 3 | 3 | 0 | 0 | 12.0 | 18 | 12 | 12 | 0 | 13 | 4 | 9.75 | 3.00 | 2.58 | 1.38 |
| C Breslow | MIN | 0 | 2 | 1.91 | 49 | 0 | 0 | 1 | 47.0 | 34 | 12 | 10 | 1 | 19 | 39 | 3.64 | 7.47 | 1.13 | 0.81 |
| A Laffey | CLE | 5 | 7 | 4.23 | 16 | 16 | 0 | 0 | 93.2 | 103 | 52 | 44 | 10 | 31 | 43 | 2.99 | 4.15 | 1.43 | 1.58 |
| S Feldman | TEX | 6 | 8 | 5.29 | 28 | 25 | 0 | 0 | 151.1 | 161 | 103 | 89 | 22 | 56 | 74 | 3.34 | 4.41 | 1.43 | 1.25 |
| B Korecky | MIN | 2 | 0 | 4.58 | 16 | 0 | 0 | 0 | 17.2 | 19 | 9 | 9 | 2 | 8 | 6 | 4.19 | 3.14 | 1.53 | 1.30 |
| J Fulchino | KC | 0 | 1 | 9.00 | 12 | 0 | 0 | 0 | 14.0 | 21 | 15 | 14 | 2 | 8 | 12 | 5.14 | 7.71 | 2.07 | 1.58 |
| D Eveland | OAK | 9 | 9 | 4.34 | 29 | 29 | 1 | 0 | 168.0 | 172 | 82 | 81 | 10 | 77 | 118 | 4.13 | 6.32 | 1.48 | 1.41 |
| J Litsch | TOR | 13 | 9 | 3.58 | 29 | 28 | 2 | 0 | 176.0 | 178 | 79 | 70 | 20 | 39 | 99 | 1.99 | 5.06 | 1.23 | 1.26 |
| S Richmond | TOR | 1 | 3 | 4.00 | 5 | 5 | 1 | 0 | 27.0 | 32 | 12 | 12 | 2 | 2 | 20 | 0.67 | 6.67 | 1.26 | 0.82 |
| B Bannister | KC | 9 | 16 | 5.76 | 32 | 32 | 1 | 0 | 182.2 | 215 | 127 | 117 | 29 | 58 | 113 | 2.86 | 5.58 | 1.49 | 0.89 |
| B Ziegler | OAK | 3 | 0 | 1.06 | 47 | 0 | 0 | 11 | 59.2 | 47 | 8 | 7 | 2 | 22 | 30 | 3.34 | 4.56 | 1.16 | 3.26 |
| E O'Flaherty | SEA | 0 | 1 | 20.25 | 7 | 0 | 0 | 0 | 6.2 | 16 | 15 | 15 | 2 | 4 | 4 | 5.81 | 5.81 | 3.00 | 2.20 |
| N Blackburn | MIN | 11 | 11 | 4.05 | 33 | 33 | 0 | 0 | 193.1 | 224 | 102 | 87 | 23 | 39 | 96 | 1.82 | 4.47 | 1.36 | 1.17 |
| K Jepsen | LAA | 0 | 1 | 4.32 | 9 | 0 | 0 | 0 | 8.1 | 8 | 5 | 4 | 0 | 4 | 7 | 4.44 | 7.78 | 1.44 | 1.25 |
| J Shields | TB | 14 | 8 | 3.56 | 33 | 33 | 3 | 0 | 215.0 | 208 | 94 | 85 | 24 | 40 | 160 | 1.67 | 6.70 | 1.15 | 1.27 |
| R Wells | TOR | 0 | 0 | 0.00 | 1 | 0 | 0 | 0 | 1.0 | 0 | 0 | 0 | 0 | 1 | 0 | 9.00 | 0.00 | 1.00 | 2.00 |
| C Rapada | DET | 3 | 0 | 4.22 | 25 | 0 | 0 | 0 | 21.1 | 19 | 11 | 10 | 0 | 14 | 15 | 5.97 | 6.40 | 1.55 | 1.35 |
| J Papelbon | BOS | 5 | 4 | 2.34 | 67 | 0 | 0 | 41 | 69.1 | 58 | 24 | 18 | 4 | 8 | 77 | 1.04 | 10.03 | 0.95 | 1.46 |
| P Neshek | MIN | 0 | 1 | 4.73 | 15 | 0 | 0 | 0 | 13.1 | 12 | 7 | 7 | 2 | 4 | 15 | 2.75 | 10.31 | 1.20 | 0.67 |
| M Lowe | SEA | 1 | 5 | 5.37 | 57 | 0 | 0 | 1 | 63.2 | 78 | 44 | 38 | 6 | 34 | 55 | 4.84 | 7.83 | 1.76 | 1.03 |
| G Perkins | MIN | 12 | 4 | 4.41 | 26 | 26 | 0 | 0 | 151.0 | 183 | 81 | 74 | 25 | 39 | 74 | 2.32 | 4.41 | 1.47 | 0.90 |
| J Weaver | LAA | 11 | 10 | 4.33 | 30 | 30 | 0 | 0 | 176.2 | 173 | 88 | 85 | 20 | 54 | 152 | 2.76 | 7.76 | 1.28 | 0.69 |
| B White | TEX | 0 | 0 | 20.25 | 8 | 0 | 0 | 0 | 4.0 | 7 | 9 | 9 | 1 | 11 | 1 | 24.75 | 2.25 | 4.50 | 0.57 |
| C Wilson | TEX | 2 | 2 | 6.02 | 50 | 0 | 0 | 24 | 46.1 | 49 | 35 | 31 | 8 | 27 | 41 | 5.27 | 8.00 | 1.64 | 1.46 |
| D Mathis | TEX | 2 | 1 | 6.85 | 8 | 4 | 0 | 0 | 22.1 | 37 | 20 | 17 | 3 | 14 | 9 | 5.70 | 3.67 | 2.28 | 1.11 |
| K Birkins | TB | 0 | 0 | 0.90 | 6 | 0 | 0 | 0 | 10.0 | 5 | 1 | 1 | 0 | 5 | 7 | 4.50 | 6.30 | 1.00 | 1.56 |
| K Gabbard | TEX | 2 | 3 | 4.82 | 12 | 12 | 0 | 0 | 56.0 | 64 | 36 | 30 | 5 | 39 | 33 | 6.27 | 5.30 | 1.84 | 2.94 |
| A Murray | TEX | 1 | 0 | 3.52 | 2 | 2 | 0 | 0 | 7.2 | 12 | 4 | 3 | 0 | 3 | 5 | 3.75 | 6.25 | 1.96 | 1.11 |
| A Galarraga | DET | 13 | 7 | 3.73 | 30 | 28 | 0 | 0 | 178.2 | 152 | 83 | 74 | 28 | 61 | 126 | 3.08 | 6.36 | 1.19 | 1.10 |
| J Zumaya | DET | 0 | 2 | 3.47 | 21 | 0 | 0 | 1 | 23.1 | 24 | 13 | 9 | 3 | 22 | 22 | 8.57 | 8.57 | 1.97 | 0.81 |
| B Slocum | CLE | 0 | 0 | 27.00 | 2 | 0 | 0 | 0 | 2.0 | 8 | 6 | 6 | 2 | 0 | 1 | 0.00 | 4.50 | 4.00 | 0.00 |
| S Gallagher | OAK | 2 | 3 | 5.88 | 11 | 11 | 0 | 0 | 56.2 | 60 | 42 | 37 | 7 | 36 | 54 | 5.77 | 8.65 | 1.69 | 0.45 |
| F Dolsi | DET | 1 | 5 | 3.97 | 42 | 0 | 0 | 2 | 47.2 | 50 | 21 | 21 | 3 | 28 | 29 | 5.34 | 5.53 | 1.64 | 1.80 |
| S Marcum | TOR | 9 | 7 | 3.39 | 25 | 25 | 0 | 0 | 151.1 | 126 | 60 | 57 | 21 | 50 | 123 | 2.98 | 7.33 | 1.16 | 1.02 |
| A Russell | CWS | 4 | 0 | 5.19 | 22 | 0 | 0 | 0 | 26.0 | 30 | 15 | 15 | 1 | 10 | 22 | 3.46 | 7.62 | 1.54 | 0.87 |
| J Albaladejo | NYY | 0 | 1 | 3.95 | 7 | 0 | 0 | 0 | 13.2 | 15 | 6 | 6 | 1 | 6 | 13 | 4.09 | 8.86 | 1.54 | 1.60 |
| J Lester | BOS | 16 | 6 | 3.21 | 33 | 33 | 2 | 0 | 210.1 | 202 | 78 | 75 | 14 | 66 | 152 | 2.83 | 6.51 | 1.27 | 1.38 |
| M Talbot | TB | 0 | 0 | 11.17 | 3 | 1 | 0 | 0 | 9.2 | 16 | 12 | 12 | 3 | 11 | 5 | 10.76 | 4.89 | 2.79 | 1.30 |
| W Littleton | TEX | 0 | 0 | 6.00 | 12 | 0 | 0 | 0 | 18.0 | 18 | 12 | 12 | 1 | 8 | 14 | 4.00 | 7.00 | 1.44 | 1.93 |
| I Kennedy | NYY | 0 | 4 | 8.17 | 10 | 9 | 0 | 0 | 39.2 | 50 | 37 | 36 | 5 | 26 | 27 | 5.97 | 6.20 | 1.92 | 0.86 |
| C Buchholz | BOS | 2 | 9 | 6.75 | 16 | 15 | 1 | 0 | 76.0 | 93 | 63 | 57 | 11 | 41 | 72 | 4.86 | 8.53 | 1.76 | 1.35 |
| B Morrow | SEA | 3 | 4 | 3.34 | 45 | 5 | 0 | 10 | 64.2 | 40 | 26 | 24 | 10 | 34 | 75 | 4.77 | 10.51 | 1.14 | 0.59 |
| C Richard | CWS | 2 | 5 | 6.04 | 13 | 8 | 0 | 0 | 47.2 | 61 | 37 | 32 | 5 | 13 | 29 | 2.48 | 5.53 | 1.55 | 1.58 |
| D Purcey | TOR | 3 | 6 | 5.54 | 12 | 12 | 1 | 0 | 65.0 | 67 | 41 | 40 | 9 | 29 | 58 | 4.02 | 8.03 | 1.48 | 0.57 |
| B McCrory | BAL | 0 | 0 | 15.63 | 8 | 0 | 0 | 0 | 6.1 | 10 | 12 | 11 | 0 | 8 | 5 | 11.80 | 7.38 | 2.84 | 1.80 |
| R Ohlendorf | NYY | 1 | 1 | 6.53 | 25 | 0 | 0 | 0 | 40.0 | 50 | 31 | 29 | 7 | 19 | 36 | 4.28 | 8.10 | 1.73 | 1.21 |
| D Price | TB | 0 | 0 | 1.93 | 5 | 1 | 0 | 0 | 14.0 | 9 | 4 | 3 | 1 | 4 | 12 | 2.57 | 7.71 | 0.93 | 1.00 |
| D Pauley | BOS | 0 | 1 | 11.68 | 6 | 2 | 0 | 0 | 12.1 | 23 | 17 | 16 | 2 | 5 | 11 | 3.72 | 8.18 | 2.27 | 1.45 |
| R Feierabend | SEA | 1 | 4 | 7.71 | 8 | 8 | 0 | 0 | 39.2 | 59 | 34 | 34 | 7 | 14 | 26 | 3.21 | 5.97 | 1.84 | 0.93 |
| S Patterson | NYY | 0 | 0 | 6.75 | 1 | 0 | 0 | 0 | 1.1 | 1 | 1 | 1 | 0 | 2 | 2 | 16.36 | 16.36 | 2.25 | 0.00 |
| J Newman | KC | 0 | 0 | 7.71 | 4 | 0 | 0 | 0 | 7.0 | 10 | 9 | 6 | 1 | 6 | 2 | 7.71 | 2.57 | 2.29 | 0.38 |
| R Cherry | BAL | 0 | 3 | 6.35 | 18 | 0 | 0 | 1 | 17.0 | 15 | 15 | 12 | 3 | 16 | 15 | 8.47 | 7.94 | 1.82 | 0.95 |
| B Logan | CWS | 2 | 3 | 5.95 | 55 | 0 | 0 | 0 | 42.1 | 57 | 31 | 28 | 7 | 14 | 42 | 2.99 | 8.98 | 1.68 | 1.18 |
| P Coke | NYY | 1 | 0 | 0.61 | 12 | 0 | 0 | 0 | 14.2 | 8 | 1 | 1 | 0 | 2 | 14 | 1.27 | 8.87 | 0.68 | 1.31 |
| J Wells | SEA | 0 | 0 | 10.13 | 6 | 0 | 0 | 0 | 5.1 | 7 | 6 | 6 | 2 | 6 | 3 | 10.59 | 5.29 | 2.44 | 1.33 |
| M Harrison | TEX | 9 | 3 | 5.49 | 15 | 15 | 1 | 0 | 83.2 | 100 | 57 | 51 | 12 | 31 | 42 | 3.35 | 4.54 | 1.57 | 1.01 |
| R Bierd | BAL | 0 | 2 | 4.91 | 29 | 0 | 0 | 0 | 36.2 | 48 | 21 | 20 | 3 | 19 | 25 | 4.72 | 6.22 | 1.83 | 0.77 |
| J Devine | OAK | 6 | 1 | 0.59 | 42 | 0 | 0 | 1 | 45.2 | 23 | 7 | 3 | 0 | 15 | 49 | 2.99 | 9.76 | 0.83 | 0.71 |
| G Olson | BAL | 9 | 10 | 6.65 | 26 | 26 | 0 | 0 | 132.2 | 168 | 100 | 98 | 17 | 62 | 83 | 4.22 | 5.65 | 1.73 | 0.91 |
| T Mastny | CLE | 2 | 2 | 10.80 | 14 | 1 | 0 | 0 | 20.0 | 28 | 24 | 24 | 6 | 11 | 19 | 4.95 | 8.55 | 1.95 | 0.68 |
| R Rundles | CLE | 0 | 0 | 1.80 | 8 | 0 | 0 | 0 | 5.0 | 5 | 1 | 1 | 0 | 3 | 6 | 5.40 | 10.80 | 1.60 | 1.25 |
| E Hurley | TEX | 1 | 2 | 5.47 | 5 | 5 | 0 | 0 | 24.2 | 26 | 15 | 15 | 5 | 9 | 13 | 3.35 | 4.83 | 1.42 | 0.34 |
| M Albers | BAL | 3 | 3 | 3.49 | 28 | 3 | 0 | 0 | 49.0 | 43 | 21 | 19 | 4 | 22 | 26 | 4.04 | 4.78 | 1.33 | 1.44 |
| H Sanchez | NYY | 0 | 0 | 4.50 | 2 | 0 | 0 | 0 | 2.0 | 1 | 1 | 1 | 0 | 2 | 1 | 9.00 | 4.50 | 1.50 | 4.00 |
| A Sonnanstine | TB | 13 | 9 | 4.38 | 32 | 32 | 1 | 0 | 193.1 | 212 | 105 | 94 | 21 | 37 | 124 | 1.72 | 5.78 | 1.29 | 0.96 |
| K Slowey | MIN | 12 | 11 | 3.99 | 27 | 27 | 3 | 0 | 160.1 | 161 | 74 | 71 | 22 | 24 | 123 | 1.35 | 6.91 | 1.15 | 0.76 |
| P Humber | MIN | 0 | 0 | 4.63 | 5 | 0 | 0 | 0 | 11.2 | 11 | 6 | 6 | 4 | 5 | 6 | 4.02 | 4.82 | 1.37 | 1.42 |
| J Meloan | CLE | 0 | 0 | 0.00 | 2 | 0 | 0 | 0 | 2.0 | 0 | 0 | 0 | 0 | 1 | 2 | 4.50 | 9.00 | 0.50 | 1.00 |
| L Hochevar | KC | 6 | 12 | 5.51 | 22 | 22 | 0 | 0 | 129.0 | 143 | 84 | 79 | 12 | 47 | 72 | 3.28 | 5.02 | 1.47 | 1.55 |
| J Lewis | CLE | 0 | 4 | 3.82 | 51 | 0 | 0 | 13 | 66.0 | 68 | 29 | 28 | 8 | 27 | 52 | 3.68 | 7.09 | 1.44 | 0.69 |
| G Smith | OAK | 7 | 16 | 4.16 | 32 | 32 | 2 | 0 | 190.1 | 169 | 92 | 88 | 21 | 87 | 111 | 4.12 | 5.26 | 1.35 | 0.69 |
| S Lewis | CLE | 4 | 0 | 2.63 | 4 | 4 | 0 | 0 | 24.0 | 20 | 9 | 7 | 4 | 6 | 15 | 2.25 | 5.63 | 1.08 | 0.76 |
| J Sowers | CLE | 4 | 9 | 5.58 | 22 | 22 | 0 | 0 | 121.0 | 141 | 84 | 75 | 18 | 39 | 64 | 2.90 | 4.76 | 1.49 | 1.18 |
| J Blevins | OAK | 1 | 3 | 3.11 | 36 | 0 | 0 | 0 | 37.2 | 32 | 14 | 13 | 2 | 13 | 35 | 3.15 | 8.47 | 1.19 | 0.81 |
| D Braden | OAK | 5 | 4 | 4.14 | 19 | 10 | 0 | 0 | 71.2 | 77 | 36 | 33 | 8 | 25 | 41 | 3.16 | 5.18 | 1.42 | 0.85 |
| C Rosa | KC | 0 | 0 | 2.70 | 2 | 0 | 0 | 0 | 3.1 | 3 | 1 | 1 | 0 | 0 | 3 | 0.00 | 8.71 | 0.90 | 0.00 |
| R Thompson | LAA | 0 | 0 | 22.50 | 2 | 0 | 0 | 0 | 2.0 | 4 | 5 | 5 | 0 | 2 | 1 | 9.00 | 4.50 | 3.00 | 0.00 |
| R Perez | CLE | 4 | 4 | 3.54 | 73 | 0 | 0 | 2 | 76.1 | 67 | 32 | 30 | 8 | 23 | 86 | 2.72 | 10.17 | 1.18 | 2.45 |
| N Musser | KC | 0 | 0 | 0.00 | 1 | 0 | 0 | 0 | 1.0 | 0 | 0 | 0 | 0 | 1 | 0 | 9.00 | 0.00 | 1.00 | 0.00 |
| J Arredondo | LAA | 10 | 2 | 1.62 | 52 | 0 | 0 | 0 | 61.0 | 42 | 15 | 11 | 3 | 22 | 55 | 3.25 | 8.11 | 1.05 | 1.41 |
| G Gonzalez | OAK | 1 | 4 | 7.68 | 10 | 7 | 0 | 0 | 34.0 | 32 | 34 | 29 | 9 | 25 | 34 | 6.62 | 9.00 | 1.68 | 1.26 |
| P Hughes | NYY | 0 | 4 | 6.62 | 8 | 8 | 0 | 0 | 34.0 | 43 | 26 | 25 | 3 | 15 | 23 | 3.97 | 6.09 | 1.71 | 0.86 |
| C Lambert | DET | 1 | 2 | 5.66 | 8 | 3 | 0 | 0 | 20.2 | 31 | 18 | 13 | 3 | 7 | 15 | 3.12 | 6.68 | 1.84 | 0.78 |
| J Miller | BAL | 0 | 2 | 1.17 | 8 | 0 | 0 | 1 | 7.2 | 9 | 3 | 1 | 0 | 5 | 8 | 6.25 | 10.00 | 1.83 | 1.67 |
| C Britton | NYY | 0 | 0 | 5.09 | 15 | 0 | 0 | 0 | 23.0 | 28 | 13 | 13 | 4 | 11 | 12 | 4.30 | 4.70 | 1.70 | 0.41 |
| J Johnson | BAL | 2 | 4 | 2.23 | 54 | 0 | 0 | 1 | 68.2 | 54 | 18 | 17 | 0 | 28 | 38 | 3.70 | 5.01 | 1.19 | 2.02 |
| J Gray | OAK | 0 | 0 | 7.71 | 5 | 0 | 0 | 0 | 4.2 | 8 | 4 | 4 | 1 | 1 | 4 | 2.14 | 8.57 | 1.93 | 1.00 |
| C Jimenez | SEA | 0 | 2 | 3.41 | 31 | 2 | 0 | 0 | 34.1 | 32 | 13 | 13 | 2 | 13 | 26 | 3.43 | 6.86 | 1.31 | 1.00 |
| E Mujica | CLE | 3 | 2 | 6.75 | 33 | 0 | 0 | 0 | 38.2 | 46 | 29 | 29 | 5 | 10 | 27 | 2.36 | 6.36 | 1.45 | 0.60 |
| J Soria | KC | 2 | 3 | 1.60 | 63 | 0 | 0 | 42 | 67.1 | 39 | 13 | 12 | 5 | 19 | 66 | 2.55 | 8.85 | 0.86 | 0.99 |
| J Salas | TB | 0 | 0 | 7.11 | 5 | 0 | 0 | 0 | 6.1 | 5 | 5 | 5 | 0 | 4 | 8 | 5.90 | 11.80 | 1.42 | 0.25 |
| J Mijares | MIN | 0 | 1 | 0.87 | 10 | 0 | 0 | 0 | 10.1 | 3 | 1 | 1 | 0 | 0 | 5 | 0.00 | 4.46 | 0.29 | 0.86 |
| F Hernandez | OAK | 1 | 0 | 18.00 | 3 | 0 | 0 | 0 | 3.0 | 4 | 6 | 6 | 0 | 5 | 2 | 15.00 | 6.00 | 3.00 | 0.17 |
| R Liz | BAL | 6 | 6 | 6.72 | 17 | 17 | 0 | 0 | 84.1 | 99 | 67 | 63 | 16 | 51 | 57 | 5.46 | 6.10 | 1.78 | 0.68 |
| C Zink | BOS | 0 | 0 | 16.62 | 1 | 1 | 0 | 0 | 4.1 | 11 | 8 | 8 | 0 | 1 | 1 | 2.20 | 2.20 | 2.77 | 0.71 |
| D Hansack | BOS | 1 | 0 | 4.05 | 4 | 0 | 0 | 0 | 6.2 | 6 | 5 | 3 | 0 | 1 | 5 | 1.45 | 7.26 | 1.05 | 1.14 |
| E Wassermann | CWS | 1 | 2 | 7.78 | 24 | 0 | 0 | 0 | 19.2 | 27 | 19 | 17 | 0 | 14 | 9 | 6.56 | 4.22 | 2.08 | 1.00 |
| A Aceves | NYY | 1 | 0 | 2.40 | 6 | 4 | 0 | 0 | 30.0 | 25 | 8 | 8 | 4 | 10 | 16 | 3.00 | 4.80 | 1.17 | 0.76 |
| E Ramirez | NYY | 5 | 1 | 3.90 | 55 | 0 | 0 | 1 | 55.1 | 44 | 25 | 24 | 7 | 24 | 63 | 3.92 | 10.29 | 1.23 | 0.59 |
| J Ryu | TB | 0 | 0 | 0.00 | 1 | 0 | 0 | 0 | 1.1 | 0 | 0 | 0 | 0 | 1 | 1 | 8.18 | 8.18 | 0.75 | 0.00 |
| L Broadway | CWS | 1 | 0 | 7.07 | 7 | 1 | 0 | 0 | 14.0 | 20 | 11 | 11 | 4 | 5 | 7 | 3.21 | 4.50 | 1.79 | 2.18 |
| C Hansen | BOS | 1 | 3 | 5.58 | 32 | 0 | 0 | 2 | 30.2 | 29 | 23 | 19 | 2 | 23 | 25 | 6.85 | 7.45 | 1.70 | 1.33 |
| J Masterson | BOS | 6 | 5 | 3.16 | 36 | 9 | 0 | 0 | 88.1 | 68 | 31 | 31 | 10 | 40 | 68 | 4.09 | 6.95 | 1.22 | 2.08 |
| J Thomas | SEA | 0 | 1 | 6.75 | 8 | 0 | 0 | 0 | 4.0 | 9 | 3 | 3 | 0 | 2 | 2 | 4.50 | 4.50 | 2.75 | 0.13 |
| M Bowden | BOS | 1 | 0 | 3.60 | 1 | 1 | 0 | 0 | 5.0 | 7 | 2 | 2 | 0 | 1 | 3 | 1.80 | 5.40 | 1.60 | 0.22 |
| T Hunter | TEX | 0 | 2 | 16.36 | 3 | 3 | 0 | 0 | 11.0 | 23 | 20 | 20 | 4 | 3 | 9 | 2.45 | 7.36 | 2.36 | 0.63 |
| J Outman | OAK | 1 | 2 | 4.56 | 6 | 4 | 0 | 0 | 25.2 | 34 | 14 | 13 | 1 | 8 | 19 | 2.86 | 6.79 | 1.64 | 0.93 |
| M Garza | TB | 11 | 9 | 3.70 | 30 | 30 | 3 | 0 | 184.2 | 170 | 83 | 76 | 19 | 59 | 128 | 2.88 | 6.25 | 1.24 | 0.92 |
| M Kobayashi | CLE | 4 | 5 | 4.53 | 57 | 0 | 0 | 6 | 55.2 | 65 | 30 | 28 | 8 | 14 | 35 | 2.28 | 5.71 | 1.42 | 1.48 |
| D Matsuzaka | BOS | 18 | 3 | 2.90 | 29 | 29 | 0 | 0 | 167.2 | 128 | 58 | 54 | 12 | 94 | 154 | 5.06 | 8.29 | 1.32 | 0.80 |
| Y Yabuta | KC | 1 | 3 | 4.78 | 31 | 0 | 0 | 0 | 37.2 | 41 | 21 | 20 | 6 | 17 | 25 | 4.11 | 6.05 | 1.54 | 1.37 |
| K Mickolio | BAL | 0 | 1 | 5.87 | 9 | 0 | 0 | 0 | 7.2 | 8 | 5 | 5 | 0 | 4 | 8 | 5.00 | 10.00 | 1.57 | 0.78 |
| J Chamberlain | NYY | 4 | 3 | 2.60 | 42 | 12 | 0 | 0 | 100.1 | 87 | 32 | 29 | 5 | 39 | 118 | 3.51 | 10.61 | 1.26 | 1.46 |
| D Robertson | NYY | 4 | 0 | 5.34 | 25 | 0 | 0 | 0 | 30.1 | 29 | 18 | 18 | 3 | 15 | 36 | 4.49 | 10.76 | 1.45 | 0.68 |
| D O'Day | LAA | 0 | 1 | 4.57 | 30 | 0 | 0 | 0 | 43.1 | 49 | 24 | 22 | 2 | 14 | 29 | 2.92 | 6.06 | 1.45 | 1.81 |
| K Fukumori | TEX | 0 | 0 | 20.25 | 4 | 0 | 0 | 0 | 4.0 | 11 | 9 | 9 | 2 | 4 | 1 | 9.00 | 2.25 | 3.75 | 0.83 |
| K Igawa | NYY | 0 | 1 | 13.50 | 2 | 1 | 0 | 0 | 4.0 | 13 | 6 | 6 | 0 | 0 | 0 | 0.00 | 0.00 | 3.25 | 0.50 |
| H Okajima | BOS | 3 | 2 | 2.61 | 64 | 0 | 0 | 1 | 62.0 | 49 | 18 | 18 | 6 | 23 | 60 | 3.34 | 8.71 | 1.16 | 0.66 |