| Pick | Overall | Team | Player | Position | School | State |
| 1 | 653 | Tampa Bay Rays | Jason Appel | OF | UNC Wilmington | N.C. |
| 2 | 654 | Pittsburgh Pirates | Patrick Palmeiro | 3B | Heritage HS, Colleyville, Texas | Texas |
| 3 | 655 | Kansas City Royals | Blaine Hardy | LHP | Lewis-Clark State (Idaho) | Idaho |
| 4 | 656 | Baltimore Orioles | Pat Kantakevich | RHP | William & Mary | Va. |
| 5 | 657 | San Francisco Giants | Carter Bell | 3B | Vanier SS, Toronto | British Columbia |
| 6 | 658 | Florida Marlins | Jared Yecker | RHP | St. John's | N.J. |
| 7 | 659 | Cincinnati Reds | Byron Wiley | OF | Kansas State | Kan. |
| 8 | 660 | Chicago White Sox | Jose Vargas | 3B | Ventura (Calif.) JC | Calif. |
| 9 | 661 | Washington Nationals | Chris Curran | 2B | Miami-Dade CC | Fla. |
| 10 | 662 | Houston Astros | Terrance Jackson | LHP | North Central Texas JC | Texas |
| 11 | 663 | Texas Rangers | Trevor Hurley | RHP | Kansas State | Kan. |
| 12 | 664 | Oakland Athletics | Preston Guilmet | RHP | Arizona | Ariz. |
| 13 | 665 | St. Louis Cardinals | Colt Sedbrook | SS | Arizona | Ariz. |
| 14 | 666 | Minnesota Twins | Kyle Witten | RHP | Bakersfield (Calif.) JC | Calif. |
| 15 | 667 | Los Angeles Dodgers | Matt Smith | RHP | Wichita State | Kan. |
| 16 | 668 | Milwaukee Brewers | Ben Jeffers | RHP | Chipola (Fla.) JC | Fla. |
| 17 | 669 | Toronto Blue Jays | Karim Turkamani | C | Miami-Dade CC | Fla. |
| 18 | 670 | Atlanta Braves | Dane Carter | 3B | Texas A&M | Texas |
| 19 | 671 | Chicago Cubs | Tarlandas Mitchell | RHP | Alto (Texas) HS | Texas |
| 20 | 672 | Seattle Mariners | Blake Nation | RHP | Georgia Southern | Ga. |
| 21 | 673 | Detroit Tigers | Zack MacPhee | SS | O'Connor HS, Phoenix | Ariz. |
| 22 | 674 | New York Mets | Chris Schwinden | RHP | Fresno Pacific (Calif.) | Calif. |
| 23 | 675 | San Diego Padres | Chris Wilkes | RHP | Dr. Phillips HS, Orlando | Fla. |
| 24 | 676 | Philadelphia Phillies | Daniel Hargrave | 2B | UNC Wilmington | N.C. |
| 25 | 677 | Colorado Rockies | Nick Schnaitmann | RHP | Cosumnes River (Calif.) JC | Calif. |
| 26 | 678 | Arizona Diamondbacks | Justin LaTempa | RHP | Golden West (Calif.) JC | Calif. |
| 27 | 679 | Los Angeles Angels | Ryan Groth | OF | Oral Roberts | Okla. |
| 28 | 680 | New York Yankees | Cory Arbiso | RHP | Cal State Fullerton | Calif. |
| 29 | 681 | Cleveland Indians | Bryce Stowell | RHP | UC Irvine | Calif. |
| 30 | 682 | Boston Red Sox | Anthony DeSclafani | RHP | Colts Neck (N.J.) HS | N.J. |