Two poor defensive plays by the U.S. helped the World take the lead with four runs in the seventh. Brett Lawrie (Brewers) led off with a sharp double to left, went to third on an infield hit by Starlin Castro (Cubs) and scored on a wild pitch by Trevor Reckling (Angels). Castro was on second base with one out when Alcides Escobar (Brewers) chopped a grounder up the middle. U.S. second baseman Jemile Weeks (Athletics) gloved the ball and tried to flip it to shortstop Danny Espinosa (Nationals) in an attempt to hold Castro at third, but the ball got way. Castro scored and Escobar took second. Reckling struck out Tyson Gillies (Mariners) looking on a curveball and gave way to Brad Lincoln (Pirates).

Pinch-hitter Rene Tosoni (Twins) doubled off the glove of first baseman Chris Carter (Athletics), who lived up to his reputation as a defensively-challenge player. Dayan Viciedo (White Sox) followed with another double, giving the World a 7-5 lead with a half-inning to go.